KABUL, Afghanistan — More than 1,000 people were killed and 1,600 others injured after a 5.9-magnitude earthquake struck a remote and mountainous region of southeastern Afghanistan near the border with Pakistan early Wednesday, officials said.
The quake struck about 28 miles southwest of the city of Khost, a provincial capital in the country’s southeast, the United States Geological Survey said, and had a depth of about six miles.
Raees Hozaifa, the director of information and culture in the eastern province of Paktika, said that 1,000 people in the province had been killed and another 1,500 injured. In Khost Province, Shabir Ahmad Osmani, the director of information and culture, said that 40 people had died and more than 100 were injured.
The United Nations’ emergency response agency said that search and rescue efforts were continuing, led by the Afghan Ministry of Defense, but that wind and heavy rain were preventing helicopters from landing and that casualties were likely to rise.
Some of the areas hit by the earthquake are in remote, rough country near the Pakistani border and were the scene of heavy fighting before and after the Taliban takeover of Afghanistan. Telecommunications are poor or nonexistent, making it hard to get a full accounting of the casualties.
Paktika is one of the country’s most sparsely populated provinces and also one of the poorest, with residents in some areas living in earthen homes. With rugged terrain and little land flat enough for farming, many people eke out a living in the forests, illegally cutting trees to sell as firewood.
Mohammad Almas, the head of aid and appeals at Qamar, a charity in Afghanistan active in the area, said he expected the death toll to be high, as the affected areas are far from hospitals and because the earthquake happened at night, when most people were indoors sleeping.
As many as 17 members of the same family were killed in one village when their home collapsed, he said; only one child survived. Mr. Almas, reached by phone from Pakistan, said that more than 25 villages were almost completely destroyed, including schools, mosques and homes.
Larisa Klepac, acting national director of humanitarian charity World Vision in Afghanistan, said she was “deeply concerned about the devastation that this earthquake causes in a country already in the grips of extreme poverty, drought and a worsening political, economic and security situation.”
The Bakhtar news agency posted video footage on Twitter of a helicopter landing in what it said was a quake-hit area. It said that ambulances were transporting the injured to hospitals.
Sarhadi Khosti, 26, who lives in the Sperah district of Khost Province, said he had been woken up by the earthquake after 1 a.m., and that a number of houses — especially those made of soil or wood — had been completely destroyed. He said that helicopters had transported some of the wounded to hospitals in Kabul and neighboring provinces.
“For now, we still are busy pulling the dead or injured from under the rubble,” he said.
Dr. Ramiz Alakbarov, a deputy special representative for Afghanistan for the United Nations, wrote on Twitter that the organization was assessing the situation in the aftermath of the earthquake. Dr. Tedros Adhanom Ghebreyesus, director general of the World Health Organization, said on Twitter that the agency would “continue supporting people in need across the country.”
The quake struck about 300 miles north-northeast of the site of a deadly 6.4-magnitude earthquake in Pakistan in 2008, the U.S.G.S. said. More than 200 people were reported killed at the time.
The earthquake was felt in Kabul, the Afghan capital, and across the northern part of neighboring Pakistan, according to a map that the European Mediterranean Seismological Center posted on its website. The U.S.G.S. said that a second quake, of 4.5 magnitude, struck about 30 miles southwest of Khost about an hour later.
Safiullah Padshah reported from Kabul, Afghanistan, and Mike Ives from Seoul. Isabella Kwai and Emma Bubola contributed reporting from London, and Salman Masood from Islamabad, Pakistan.